ARA-290

ARA-290 — Research Use Only ARA-290, also known as cibinetide or pyroglutamate helix-B surface peptide, is a synthetic 11-amino-acid peptide modeled from the three-dimensional structure of helix B of erythropoietin. It was engineered to study proposed tissue-protective signaling without producing erythropoietin’s red-blood-cell-forming activity. ARA-290 is used in qualified research settings to examine innate repair receptor signaling, cellular stress responses, inflammatory pathways, neuronal models, microvascular biology, and experimental tissue-protection mechanisms. Product Information Product: ARA-290 Alternative name: Cibinetide Compound type: Synthetic erythropoietin-derived peptide Peptide length: 11 amino acids Sequence: Pyr–Glu–Gln–Leu–Glu–Arg–Ala–Leu–Asn–Ser–Ser–OH Molecular formula: C₅₁H₈₄N₁₆O₂₁ Research designation: Pyroglutamate helix-B surface peptide Form: Lyophilized research material Purity: Refer to the lot-specific Certificate of Analysis Testing: Identity and purity documentation available by lot Storage: Store according to the conditions printed on the product label and Certificate of Analysis Research Applications ARA-290 may be used in qualified laboratory investigations involving: Proposed innate repair receptor signaling EPOR/CD131 receptor-complex models Cellular stress and survival pathways Inflammatory and immune-cell signaling Peripheral-neuron and sensory-pathway models Microvascular and endothelial-cell research Experimental tissue-protection mechanisms Ischemia and reperfusion models Comparative erythropoietin-derived peptide studies Non-erythropoietic signaling pathways Important Notice For research use only. Not for human or veterinary use. This product is supplied exclusively for controlled laboratory research by qualified professionals. It is not a drug, dietary supplement, or medical treatment and has not been approved by the U.S. Food and Drug Administration for clinical use. No dosing, reconstitution, administration, pain-relief, nerve-repair, anti-inflammatory, or therapeutic guidance is provided or implied. Researchers are responsible for appropriate handling and compliance with all applicable requirements.