GLP-2

A synthetic, modified 39-amino-acid peptide that acts as a dual agonist of the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R). Its structure includes a fatty-acid modification that influences albumin binding and its pharmacological properties. Laboratory and preclinical research has examined GLP-2 in experimental models involving incretin-receptor activity, intracellular signaling, pancreatic beta-cell responses, glucose-dependent insulin secretion, and metabolic regulation. Published findings do not establish the safety, efficacy, or suitability of this research-use material for human use. Product Information Product: GLP-2 Research designation: LY3298176 Compound type: Synthetic, modified peptide Peptide length: 39 amino acids Receptor targets: GIPR and GLP-1R Form: Refer to the product-specific specifications Purity: Refer to the product-specific Certificate of Analysis Testing: Refer to the product-specific Certificate of Analysis for documented testing methods and results Storage: Store according to the supplied handling documentation Research Applications commonly investigated in connection with: Dual GIPR and GLP-1R activation Incretin-receptor binding and selectivity Cyclic AMP signaling Receptor internalization and signaling bias Pancreatic beta-cell response models Glucose-dependent insulin-secretion pathways Cellular and systemic metabolic regulation Comparative studies of single- and dual-receptor agonists Important Notice This product is sold exclusively for laboratory research and analytical purposes. It is not supplied as a drug, dietary supplement, food, cosmetic, or medical product. FOR RESEARCH PURPOSES ONLY. NOT FOR HUMAN OR VETERINARY USE. NOT FOR HUMAN CONSUMPTION. This research material is not an FDA-approved finished prescription product and must not be substituted for one. This product is not intended to diagnose, treat, cure, mitigate, or prevent any disease. No dosing, administration, weight-management, blood-glucose-management, or therapeutic guidance is provided. Purchasers are responsible for ensuring that possession, handling, and research activities comply with all applicable laws, regulations, and institutional requirements.